Panax notoginseng Suppresses Bone Morphogenetic Protein-2Expression in EA.hy926 Endothelial Cells by Inhibiting theNoncanonical NF-B and Wnt/-Catenin Signaling Pathways

 PNWE decreased the W/BGP-induced oxidative stress and inflammatory response and inhibited NF-κB and Wnt/β-catenin signaling, leading to the suppression of BMP-2 transcription and expression. This result means that PNWE has the potential to alleviate the risk of VC by reducing BMP-2 expression.